Instructions

1. Stem cell exhaustion is a hallmark of aging

TRUE or False

2. Aging has a genetic component. Which of the following provides support for this idea?

a. small animals have short life spans

b. mutants can be isolated with longer life spans

c. caloric restriction extends life span

d. Aged stem cells have limited self renewal

3. Reactive oxygen species (ROS) damage macromolecules during aging.

True of False

4. In progeria, a single base change results in a truncated protein. However, the mutation is silent. What could account for this?

a. The observation that all patients with progeria have new mutations

b. The mutation causes incorrect splicing

c. The mutation changes the codon to a stop codon

Please answer these asap. Thank you

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