Which molecules contribute the nitrogen atoms for purine biosynthesis and which reactions in the de novo synthesis of purine nucleotides require energy expenditure?

identify a genetic disease that results from an anomaly associated with the biosynthesis of amino acids, nucleotides or related molecules. Provide the name of the disease, its exact biochemical effect on the pathway(s), the resultant physiological and symptomatic aspects, and how it might be treated. Provide reference.

List the compounds used as energy sources by each of the following: a) Skeletal muscle b) Cardiac muscle c) Brain

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