Instructions

Which of the following is not a destination for vesicles leaving the Golgi apparatus? a. The plasma membrane b. The exterior of the cell c. Lysosomes d. Mitochondria 8. GPl-anchored proteins are synthesized a. on free ribosomes and attached to the GPI group on the outside of the ER. b. as transmembrane proteins, cleaved, and attached to the GPI group on the cytosolic surface of the ER. c. as transmembrane proteins, cleaved, and attached to the GPI group on the lumenal surface of the ER. d. on free ribosomes and attached to the GPI group on the cytosolic surface of the ER 9. The unfolded protein response involves a. general inhibition of protein synthesis b. increased synthesis of chaperones. c. increased activity of proteosomes. d. All of the above 10. Which of the following proteins do not pass through the Golgi apparatus? a. Lysosomal enzymes b. Cell surface proteins c. Ribosomal proteins d. Proteins secreted by exocytosis 11. Which of the following classes of lipids is synthesized in the a. Phospholipids b. Glycolipids c. Cholesterol d. Ceramide 12. Brain tissue is useful for studies of vesicular transport a. many brain diseases involve mutant vesicular transoort b. synaptic ve for biochemical analysis. sicles are abundant in the brain and can be isolated in la rge quantities c. the mechanisms of vesicle transport and fusion d. All of the above and fusion are unique to neurons. 13. Lysosomes digest a. proteins. b. nucleic acid. c. carbohydrates. d. All of the above 14. The pH inside lysosomes is about a. 7.0 b. 6.0 c. 5.0 d. 4.0

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