Instructions

Explain how a genetic association study works and describe how this type of study design is scaled up to achieve a genome-wide association study (GWAS).

Describe the approaches and techniques used to generate the first draft of the human genome sequence in Feb 2001. essay style 2 pages

Describe the accessory and regulatory roles of non-protein coding RNAs in the human genome. Include diagrams to illustrate your answer. essay style and diagrams essential

Discuss how single base substitutions in DNA sequence can potentially cause a variety of functional impacts on the amino acid sequence of a protein, and describe a human disease caused by a specific single base substitution mutation.

State the functions of gonadotropin releasing hormone, follicle stimulating hormone, luteinizing hormone, inhibin, estrogen and progesterone in the female.

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