Explain the advantages and disadvantages of the uniqueness of protein structure. How does it contribute to the existence and function of organisms? Give detailed examples of the advantages and disadvantages.
Problem: Watch Your Sugar Level! The most common signs and symptoms of diabetes include excessive thirst, frequent urination, increased appetite, unexplained weight loss, fatigue, blurred vision, tingling and numb- ness in the hands or feet, slow healing wounds, and frequent infections. (Footnote] If your fasting blood glucose level is between 5.5mmol/L (100mg/dL) and 6.9mmol/L (126mg/dL), you are considered to have prediabetes (impaired fasting glucose), and you have an increased chance of developing diabetes. The Canadian Diabetes Association (CDA) criteria for diagnosing diabetes are met when any of the following results have been repeated on at least two different days: • A fasting blood glucose level is 7.Romola/L (126mg/dL) or higher. • A 2-hour oral glucose tolerance test result is 11.1 mmol/L (200mg/dL) or higher. • Symptoms of diabetes are present and a random blood glucose test is 11.1 mmol/L (200mg/dL) or higher. The fasting blood glucose level of a randomly selected person was measured for seven days and the following readings were made: 7.0, 7.7, 6.8, 7.1, 7.1,6.1,7.3. It is reasonable to assume the glucose level distribution is normal. 2. At a diabetic clinic, a group of people considered to have prediabetes (impaired fasting glucose) were ran- domly selected. Then they were randomly assigned in two groups, namely treatment group (subject to a strict diet plan) and placebo (normal diet), for a specified number of days. After the completion of the clinical trial, their blood glucose level readings provided the following statistics: ni = Placebo 10 11 = 6.5 si = 0.21 Treatment ng = 10 9 = 5.4 = 0.17 Assume the assumption of normality is satisfied. (a) Is it reasonable to assume equality of variances in this problem? Justify your answer with an appropriate test of hypothesis with a level of significance a = 0.1(you can calculate the critical value or the p-value using SPSS). (b) Do the data provide sufficient evidence at the 5% significance level that the strict diet plan lowers the blood glucose level? What is the appropriate conclusion? (e) Using SPSS, find the p – value for the test. (d) Using the p – value approach and a = 0.01, what conclusion can be drawn about the difference in average blood glucose level readings between treatment and placebo groups? (e) Estimate with 95% confidence the difference in mean blood glucose levels between the two groups. Interpret the interval estimate.
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