Instructions

Give the top view of the protein that is made up of 6 helices , 1 all hydrophobic, 3 of them 50% hydrophobic, 2 of them are 25% Hydrophobic. 17. Give the top view of the protein that is made up of 5 helices , 2 helices are 25% Hydrophobic and the other 3 are 50% Hydrophobic. 18. For the given Beta sheet sequence Ala Tyr Val Gin lle Ala Ser a single point mutation causes this sheet to break. From which amino acid it would most likely break? UFFFF Reminder Glycine mutations break the beta sheets. 19. Which force works against protein folding? 20. Tight packing ( globular) structure of the protein is caused by which force? Use the given scores in the Homework for alignment Match=6 Mismatch =-3 Gap=-4

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