Give an example of (A) G protein-coupled receptor (GPCR) and (B) Receptor Tyrosine Kinase (RTK) signalling pathways. For one of these pathways describe the steps involved from receptor activation to the activation of transcription. 2. Unlike eukaryotic cells, prokaryotic cells do not have a nucleus. Discuss briefly two or more possible benefits of the evolution of a nucleus in eukaryotes? 3. Name the four different types of microtubules that play a key role in the anaphase stage of mitosis. Briefly describe the role of each type. 4. Describe some of the genetic features and practical advantages for one prokaryotic and two eukaryotic model systems commonly used in research. 5. Give an example of a growth factor receptor and describe the steps involved from receptor activation to initiation of the cell cycle. 6. Describe the process of DNA replication in Escherichia coli including in your answer a diagram depicting the protein and enzymatic activity at the replication fork. 7. Explain how actin filaments are assembled,stabilised and disassembled.

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