Instructions

How are the T-cells activated to respond to a pathogen? Where in the body are the T-cells activated? 6. When a Helper T-cell is activated, what happens next in the immune response? 7. When a Cytotoxic T-cell is activated, what happens next in the immune response? Part 2: Follow-up of Case Study We introduced the case of a 7 month-old infant with recurrent bacterial infections such as, Staphylococcus aureus sepsis, hepatosplenomegaly, and oral thrush from Candida albicans. She most recently has been admitted to the ER with a lung infection and Staphylococcus aureus in her blood. The patient has WBC counts (59,000/mm3) and a higher than normal population of neutrophils. 1. Further tests reveal that the patient has Leukocyte adhesion deficiency (LAD). What is LAD? 2. How does LAD impact the function of the immune response?

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