Instructions

Which of the following statements about the bZIP eukaryotic transcriptional factor GCN4 (showing 52 of 281 residues for each subunit of this homodimer) binding to a 19 bp DNA segment containing is NOT correct? с 3′ 3′ 5′ B 5 N a. b. the A arrow points to a coiled coil motif that mediates dimerization the A arrow points to a leucine zipper motif characterized by amino acid residues with hydrophobic side-chains at the a position and leucine amino acid residues at the d position of a heptad repeat (a-g) the B arrow points to an alpha helical region that makes contact with specific bases in the target sequence of DNA c. a. b. c. the A arrow points to a coiled coil motif that mediates dimerization the A arrow points to a leucine zipper motif characterized by amino acid residues with hydrophobic side-chains at the a position and leucine amino acid residues at the d position of a heptad repeat (a-g) the B arrow points to an alpha helical region that makes contact with specific bases in the target sequence of DNA the B arrow points to the alpha helical region that contains basic residues that make H-bonds with specific nitrogenous bases of DNA and interact with the phosphate backbone the N-terminal alpha helical region of GCN4 makes contact with nitrogenous bases in the minor grooves on each side of the DNA duplex d. e. ОА OE

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