Instructions

. What do you expect for cancer cells and growth factor requirement for mitosis? Consider multiple ways this could differ for cancer cells based on what you have learned this semester 2. What do you expect for cancer cells and apoptosis mechanisms? How could it be impacted based on what you know? 3. Do you expect cancer cells to follow the same rules as normal cells for proliferation? First google the following properties for NORMAL cells and then think about what might differ for cancer cells. Density-dependent inhibition in culture Contact Inhibition in culture Telomeres and telomerase activity with repeated mitosis 4. Do you expect cancer cells to have a more or less stable genome? Why or why not? Relate to cell cycle info we covered. 5. What properties would make a cancer tumor more invasive/increase metastasis? Hint: think of extracellular matrix components and ways to travel in body 6. Do you expect cancer cells to survive in a new tissue location? Why or why not? 7. What do you expect for cancer cells and their state of differentiation?

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